Preventive coronary intervention at Chonnam National University Hospital and lower death and hospitalization rates than drug treatment
Jun 08, 2025
A paper published by professors Kim Min-cheol and Ahn Young-geun of the Department of Circulatory Mechanism at Chonnam National University Hospital was published in the world-renowned European Journal of Cardiology.
Professor Kim Min-cheol (first author) and Professor Ahn Young-geun (corresponding author) 'Preventive Percutaneous Coronary Intervention for Vulnerable atherosclerotic coronary plaque without impaired blood flow in diabetic patients: PREVENT Clinical Trial (PREVENT Clinical Trials: The European Heart Journal (IF 38.1)'
This study was based on a multi-center and randomized clinical study of PREVENT (Preventive Coronary Intervention with Functionally Insignificant Vulcanized Plaque) for stenosis with weak plaque that is not functionally important. We compared the two-year clinical results of preventive coronary intervention and drug treatment when diabetic patients do not have blood flow disorders, but coronary imaging shows a highly vulnerable plaque with severe arteriosclerosis.
The research team confirmed that in both diabetic and non-diabetic patients, preventive coronary intervention significantly reduced the frequency of hospitalization due to two years of psychogenic death, targeted vascular-related myocardial infarction, or worsening symptoms of coronary artery reopening and angina associated with ischemic induction compared to drug treatment.
The research team expects clinical significance of preventive cardiovascular intervention in lesions including vulnerable sclerosis with severe arteriosclerosis and results of clinical studies in a wider range of patients in the future" he said.
Meanwhile, Professor Kim Min-cheol and Ahn Young-geun's team are preparing to announce the results of a randomized study of 'OPTION-STEMI' that determines the appropriate timing of non-causal vascular treatment using FFR (Fractional flow reserve) in patients with acute ST-segment elevation myocardial infarction accompanied by multi-vascular disease for the first time in the world along with 20 major cardiovascular centers nationwide. When the results of the study are published, it is expected to provide important information for treatment decisions of patients with acute myocardial infarction with poor prognosis.
Professor Kim Min-cheol (first author) and Professor Ahn Young-geun (corresponding author) 'Preventive Percutaneous Coronary Intervention for Vulnerable atherosclerotic coronary plaque without impaired blood flow in diabetic patients: PREVENT Clinical Trial (PREVENT Clinical Trials: The European Heart Journal (IF 38.1)'
This study was based on a multi-center and randomized clinical study of PREVENT (Preventive Coronary Intervention with Functionally Insignificant Vulcanized Plaque) for stenosis with weak plaque that is not functionally important. We compared the two-year clinical results of preventive coronary intervention and drug treatment when diabetic patients do not have blood flow disorders, but coronary imaging shows a highly vulnerable plaque with severe arteriosclerosis.
The research team confirmed that in both diabetic and non-diabetic patients, preventive coronary intervention significantly reduced the frequency of hospitalization due to two years of psychogenic death, targeted vascular-related myocardial infarction, or worsening symptoms of coronary artery reopening and angina associated with ischemic induction compared to drug treatment.
The research team expects clinical significance of preventive cardiovascular intervention in lesions including vulnerable sclerosis with severe arteriosclerosis and results of clinical studies in a wider range of patients in the future" he said.
Meanwhile, Professor Kim Min-cheol and Ahn Young-geun's team are preparing to announce the results of a randomized study of 'OPTION-STEMI' that determines the appropriate timing of non-causal vascular treatment using FFR (Fractional flow reserve) in patients with acute ST-segment elevation myocardial infarction accompanied by multi-vascular disease for the first time in the world along with 20 major cardiovascular centers nationwide. When the results of the study are published, it is expected to provide important information for treatment decisions of patients with acute myocardial infarction with poor prognosis.
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This article was translated by Naver AI translator.
