Those who have experienced acute myocardial infarction have a 1.49 times higher risk of developing blood cancer

Jun 09, 2025

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A study has shown that patients who have experienced acute myocardial infarction have a higher risk of developing blood cancer than those who have no history of acute myocardial infarction.

Kwon Sung-soon, a professor of cardiology at Soonchunhyang University Seoul Hospital, and Yoon Seok-yoon, a professor of oncology, recently published in the Journal of the American Heart Association (JACC: CardioOncology) 'The Risk of Blood Cancer in Patients with Acute Myocardial Infarction: A Nationwide Population-Based Cohort Study'.

Professor Kwon Sung-soon and Yoon Seok-yoon's team compared 103,686 people diagnosed with acute myocardial infarction from 2003 to the end of 2021 with 103,686 controls matched by age/gender using the National Health Insurance Corporation claim data.

As a result of the analysis, the group who experienced acute myocardial infarction had a higher risk of developing blood cancer than the control group (1.49 times the risk ratio), and the sensitivity analysis and standardized incidence analysis corrected for various confounding variables showed consistent results.

Professor Kwon Sung-soon said, `Acute myocardial infarction and blood cancer are the main causes of death, but the relationship between the two diseases has not been clearly identified, so the study was conducted"As the results of the study, the possibility of blood cancer should be considered when long-term follow-up of patients with acute myocardial infarction "

Professor Yoon Seok-yoon "Clonal hematopoiesis', which is drawing attention as a risk factor for patients with acute myocardial infarction, is also closely related to blood cancer, so I hypothesized that the incidence of blood cancer in patients with acute myocardial infarction could increase and conducted the study."I would like to thank the Korean Society of Cardiology and Oncology Research Society for its help in the research."

Meanwhile, Professor Sung-soon Kwon, the corresponding author of the paper, and Professor Yoon Seok-yoon, the first author, were also selected by the Biological Research Information Center (BRIC) 'People Who Shined Korea (Hanbitsa).' BRIC selects Korean researchers who publish life science-related papers in global journals based on the Journal Citation Report (JCR), the citation index of 10 or higher, or within the top 3% of the field as 'Hanbitsa' every year.