Development of probiotic complex strains effective in improving osteoporosis
Jun 10, 2025
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Focusing on the close connection between intestinal microbes and bone health, the research team conducted an experiment using an animal model in which osteoporosis was induced after menopause.
As a result, the oral-administered complex strain showed a positive effect on improving bone density and structure, and the effect of improving osteoporosis was also evident in micro-CT analysis, tissue staining, and blood biomarker analysis.
In particular, better effects were confirmed when complex strains were administered than when the same amount of single strains was administered, and synergies between strains with different mechanisms of action were analyzed as the main cause.
The research results were recently published in the global scientific journal 『Scientific Reports』, a sister journal of 『Nature』, and related technologies are also pursuing domestic patent applications and industrial technology transfer.
Professor Jeong Jae-hoon "This study was carried out in collaboration with Professor Moon Ki-sung's research team at the Korea Transportation University, and we are currently conducting follow-up studies to identify more precise mechanisms of action through intestinal microbiome analysis.".
This study was conducted with support from the Ministry of Education's University-focused Research Institute Support Project, the Ministry of Science and ICT's Basic Research Support Project, and Soonchunhyang University Research Fund.
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This article was translated by Naver AI translator.
