Metformin, Hugo Bee, Fat Stem Cells, and Effect in the Low-Slow Aging Trend?
Jun 09, 2025
Anti-aging, which encompasses slow aging and reverse aging that youth cells, has become a health trend. While attention is also being paid to the medical approach to anti-aging, metformin, gastroparesis, and adipose stem cell procedures are mentioned as the medical approaches of anti-aging that are the most notable in the medical world.
Metformin and Hugo Bee have been developed as treatments for diabetes and obesity, but they are attracting attention as they are known to have anti-aging effects. Fat stem cells also show excellent effects on skin regeneration and prevention of aging and are recognized for their value in the field of regenerative medicine.
We found out how they work on our skin to prevent aging and whether they can be a realistic anti-aging alternative through expert advice.
◇Metformin emerges as an 'anti-aging pioneer' in diabetes drugs
Metformin, which was released as a treatment for type 2 diabetes, has emerged as a pioneer in anti-aging treatment as a series of studies have shown that it regulates cell metabolism and blocks inflammatory pathways related to aging.
Metformin activates AMPK, an enzyme that regulates cell metabolism, promoting skin regeneration and reducing inflammation. Activation of AMPK is reported to play an important role in promoting collagen synthesis and maintaining skin elasticity.
However, the US Food and Drug Administration (FDA) has not yet officially approved the use for anti-aging purposes. Even in Korea, metformin cannot be prescribed for the purpose of preventing aging. This is a prescription drug and can only be obtained by medical staff's prescription for patients with diseases such as type 2 diabetes and polycystic ovary syndrome.
Lee Seon-ho, head of the representative hospital (family medicine specialist) at Global 365mc Daejeon Hospital, said "Metformin has reported side effects such as nausea, diarrhea, abdominal bloating, and lactic acidosis."It is a drug that has been proven to be safe, but since it has been introduced as a treatment for diabetes, approaches other than those with related diseases should be avoided."
◇Wigobi, a medicine that keeps you young from losing weight?
Famous for 'fat-loss injections', Hugo Bee is originally a medicine for obesity. However, according to recent studies, it is noted that body fat reduction induces various anti-aging effects, such as suppressing systemic inflammation and improving cardiovascular function.
According to Harvard Medical School and Novo Nordisk joint researchers, the manufacturer of WeGovi, 'semaglutide', the main component of WeGovi, slows aging and reduces mortality from all causes, including cardiovascular or non-cardiovascular diseases, by 19%.
As aging is most related to inflammation, experts say that reducing the burden of disease has contributed positively to aging.
The head of the representative hospital Lee said, "'semaglutide', which is the main component of gastric obesity, incidentally caused the anti-aging effect while reducing the risk of diseases such as cardiovascular disease and arthritis.' `At the same time, it is recommended to administer medication only to obese patients because it can be accompanied by side effects such as gastrointestinal disease, pancreatitis, and cholelithiasis.'
Hugo Bee is also a prescription drug that requires medical staff's prescription. In Korea, obese patients with a body mass index (BMI) of 30 or higher or those with high blood pressure, diabetes, and cardiovascular disease are allowed to be prescribed.
◇fat stem cells, "Anti-aging method that anyone can experience"
Stem cell procedures using autologous fat can be performed relatively simply through medical treatment. In addition, unlike prescription drugs, it is attracting attention as a sustainable anti-aging solution in that it can perform anti-aging procedures and induces cell regeneration by using autologous tissues.
The procedure is performed by injecting stem cells extracted from fat extracted through liposuction from the thighs and abdomen into the skin. Fat is the largest reservoir of stem cells, with about 500 times more cells than bone marrow and 25,000 times more cells than peripheral blood.
Adipose stem cells have various medical possibilities, such as repairing damaged tissues and alleviating inflammatory responses while promoting angiogenesis. In particular, it stands out for skin aging. This is because it helps the tissues and cells around the skin layer to increase skin elasticity and improve wrinkles.
Lee, the head of the representative hospital, said, `Thanks to simple procedures, low risk of side effects, and accessibility that does not require hospitalization, adipose stem cell procedures are quickly becoming an 'anti-aging method for anyone to experience'"As fat stem cells contribute not only to beauty effects such as preventing aging, but also to solving future human health problems, the related market will continue to grow."
Metformin and Hugo Bee have been developed as treatments for diabetes and obesity, but they are attracting attention as they are known to have anti-aging effects. Fat stem cells also show excellent effects on skin regeneration and prevention of aging and are recognized for their value in the field of regenerative medicine.
We found out how they work on our skin to prevent aging and whether they can be a realistic anti-aging alternative through expert advice.
◇Metformin emerges as an 'anti-aging pioneer' in diabetes drugs
Metformin, which was released as a treatment for type 2 diabetes, has emerged as a pioneer in anti-aging treatment as a series of studies have shown that it regulates cell metabolism and blocks inflammatory pathways related to aging.
Metformin activates AMPK, an enzyme that regulates cell metabolism, promoting skin regeneration and reducing inflammation. Activation of AMPK is reported to play an important role in promoting collagen synthesis and maintaining skin elasticity.
However, the US Food and Drug Administration (FDA) has not yet officially approved the use for anti-aging purposes. Even in Korea, metformin cannot be prescribed for the purpose of preventing aging. This is a prescription drug and can only be obtained by medical staff's prescription for patients with diseases such as type 2 diabetes and polycystic ovary syndrome.
Lee Seon-ho, head of the representative hospital (family medicine specialist) at Global 365mc Daejeon Hospital, said "Metformin has reported side effects such as nausea, diarrhea, abdominal bloating, and lactic acidosis."It is a drug that has been proven to be safe, but since it has been introduced as a treatment for diabetes, approaches other than those with related diseases should be avoided."
◇Wigobi, a medicine that keeps you young from losing weight?
Famous for 'fat-loss injections', Hugo Bee is originally a medicine for obesity. However, according to recent studies, it is noted that body fat reduction induces various anti-aging effects, such as suppressing systemic inflammation and improving cardiovascular function.
According to Harvard Medical School and Novo Nordisk joint researchers, the manufacturer of WeGovi, 'semaglutide', the main component of WeGovi, slows aging and reduces mortality from all causes, including cardiovascular or non-cardiovascular diseases, by 19%.
As aging is most related to inflammation, experts say that reducing the burden of disease has contributed positively to aging.
The head of the representative hospital Lee said, "'semaglutide', which is the main component of gastric obesity, incidentally caused the anti-aging effect while reducing the risk of diseases such as cardiovascular disease and arthritis.' `At the same time, it is recommended to administer medication only to obese patients because it can be accompanied by side effects such as gastrointestinal disease, pancreatitis, and cholelithiasis.'
Hugo Bee is also a prescription drug that requires medical staff's prescription. In Korea, obese patients with a body mass index (BMI) of 30 or higher or those with high blood pressure, diabetes, and cardiovascular disease are allowed to be prescribed.
◇fat stem cells, "Anti-aging method that anyone can experience"
Stem cell procedures using autologous fat can be performed relatively simply through medical treatment. In addition, unlike prescription drugs, it is attracting attention as a sustainable anti-aging solution in that it can perform anti-aging procedures and induces cell regeneration by using autologous tissues.
The procedure is performed by injecting stem cells extracted from fat extracted through liposuction from the thighs and abdomen into the skin. Fat is the largest reservoir of stem cells, with about 500 times more cells than bone marrow and 25,000 times more cells than peripheral blood.
Adipose stem cells have various medical possibilities, such as repairing damaged tissues and alleviating inflammatory responses while promoting angiogenesis. In particular, it stands out for skin aging. This is because it helps the tissues and cells around the skin layer to increase skin elasticity and improve wrinkles.
Lee, the head of the representative hospital, said, `Thanks to simple procedures, low risk of side effects, and accessibility that does not require hospitalization, adipose stem cell procedures are quickly becoming an 'anti-aging method for anyone to experience'"As fat stem cells contribute not only to beauty effects such as preventing aging, but also to solving future human health problems, the related market will continue to grow."
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This article was translated by Naver AI translator.
