If you repeat ulcers and eye inflammation around your mouth and genital organs, you should suspect this disease
Sep 10, 2025
|
Typical symptoms of Becchett's disease are ulcers around the mouth and genitalia, eye inflammation (glucitis), and skin rash. Swelling and painful knee or ankle joints, or inflammation of the intestines may cause abdominal pain or diarrhea.
Professor Jeong emphasized that "Different people have different symptoms, and they show symptoms similar to other diseases such as lupus, Crohn's disease, and simple uveitis, making it difficult to diagnose" and "If inflammation is repeated in several areas, specialized treatment is required.'
It is known that various factors such as genetic predisposition, overexpression of the immune system, and intestinal bacterial imbalance act as the cause of Bethett's disease. The risk of developing is high, especially if you have the 'HLA-B51' gene, but this gene alone does not cause development. Fundamentally, the main reason is that excessive inflammatory reactions occur due to insufficient immune system control functions.
The prevalence rate in Korea is 10 to 15 per 100,000 people, which is high worldwide. It occurs mainly in young adults in their 20s and 40s, and male patients tend to show more severe symptoms than women.
Bechet's disease can be fatal if complications arise. If uveitis in the eye is repeated, it can progress to retinal vasculitis, causing damage to the macula and loss of vision. There is a risk that ulcers in the intestine can lead to bleeding or perforation of the intestine. Vascular inflammation can lead to pulmonary embolism or stroke by causing blood clots (blood cakes), and in rare cases, it invades the nervous system and causes symptoms such as paralysis or convulsions.
Treatment is centered on medication. Steroids, immunosuppressants, and oral ulcer relief agents that reduce inflammation are used. Professor Jeong advised that `To increase the effectiveness of treatment, it is important to reduce stress and fatigue, and hygiene management to prevent infectious diseases, especially during immunosuppressive treatment.' `If you have symptoms in your eyes or intestines, it is recommended to receive regular treatment through ophthalmology or gastroenterology consultations.'
Professor Jeong then said "Since the imbalance of oral and intestinal microorganisms also plays an important role in the development and symptom deterioration of Bethe's disease, it can also be helpful to combine diet or supplements (probiotics, prebiotics, postbiotics, etc.) that restore the intestinal environment close to the microbial composition of a healthy person."
Betchett's disease is a chronic disease that is difficult to cure, but symptoms can be controlled and maintained daily life through early diagnosis and constant treatment.
Professor Chung said, `If the symptoms of inflammation are repeated, do not leave them unattended and seek early treatment"Steady drug use and lifestyle management determine the quality of life of patients" he stressed.
|
This article was translated by Naver AI translator.
