Long-term melatonin supplements to relieve insomnia have a 90% higher risk of heart failure
Nov 05, 2025
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The results of the study were presented at the American Heart Association (AHA) 2025 annual conference on the 4th (local time).
The researchers analyzed the health records of about 130,000 people over five years. As a result, people who took melatonin consistently for more than a year were about 90% more likely to diagnose heart failure, and hospitalization rates increased by more than 3.5 times. It also found that people who took it daily had almost twice the risk of death.
Dr. Ekenedichuku Nnadi, who led the study, explained that "the results show that melatonin supplements, which can be purchased without prescription, should not be taken for a long time without caution.'
However, experts emphasized that this result does not mean that melatonin directly causes heart failure.
Rather, the habit of taking melatonin every day itself suggests that there is already a possibility of heart health problems.
It is analyzed that underlying diseases such as insomnia, depression, and anxiety may be associated with taking melatonin, which may be a risk factor for heart disease.
Heart failure is a condition in which the heart does not supply enough blood for the body, and chronic sleep deprivation or lifestyle can be the main cause.
According to local media such as the New York Post, more than 5 million adults in the United States are taking melatonin, and this supplement is commonly known as a safe sleep aid. However, since it is not regulated by the U.S. Food and Drug Administration (FDA), caution is needed as ingredients and doses may vary from product to product.
Experts warn that taking melatonin daily is not advisable and should not be used as a long-term solution to treat insomnia.
This article was translated by Naver AI translator.
