There is no difference in stroke risk between Moyamoya's mother, natural delivery, and cesarean section...Korea's First Large-Scale Analysis
Nov 06, 2025
A research team led by Professor Jeong Jin-man of the Department of Neurology at Korea University Ansan Hospital and Professor Kim Ho-yeon of Obstetrics and Gynecology (co-researcher Professor Lee Sang-heon of Neurology, Professor Kim Jong-heon of Neurology, and Professor Song Kwan-seop of Obstetrics and Gynecology) won the 'Best Poster Award' at the 111th conference of the Korean Society of Obstetrics and Gynecology.
The Korean Society of Obstetricians and Gynecologists is the most prestigious academic conference in the field of obstetrics and gynecologists and researchers across the country share the latest medical knowledge. This year's conference was held at the Raum Art Center in Seoul from October 30 to 31, and obstetricians and related people from all over the world attended to share the latest research results and clinical experiences in the field of obstetrics and gynecology.
The risk of stroke risk associated with the mode of delivery in women with Moyamoya disease, published by the research team, is a nationwide large-scale study comparing natural delivery and cesarean section of 1,683 mothers diagnosed with Moyamoya disease through data from the Health Insurance Review and Assessment Service from 2002 to 2023.
The study was conducted through close collaboration between neurology and obstetrics and gynecology, and by analyzing hemodynamic changes and neurological risk factors in pregnancy and delivery together, an integrated clinical basis that is difficult to obtain with a single medical department study was confirmed.
Until now, there has been no clear standard for delivery methods for mothers with moya molya disease, but cesarean section has tended to be preferred due to concerns about the risk of stroke due to changes in blood pressure during the delivery process. However, as a result of this study, there was no statistically significant difference in the risk of postpartum stroke between the two delivery methods.
This suggests the clinical basis that if proper prenatal management and monitoring are performed, mothers with moyamoya disease can also give birth naturally. In particular, this study is significant in that neurology and obstetrics jointly analyze and interpret patient data, comprehensively considering not only obstetric conditions but also cerebrovascular disease characteristics and risk factors.
In addition, the research team confirmed similar results in the analysis of age, comorbidities such as high blood pressure and diabetes, and pregnancy-related complications, supporting that there is low evidence for cesarean section just because Moya moya disease exists. The results of the study are expected to contribute to improving the guidelines for establishing customized delivery strategies for mothers with rare diseases in the future.
Professor Jeong Jin-man said, "Moya moya disease is a rare and incurable disease in which the blood vessels of the brain gradually narrow, and the risk of stroke during pregnancy and delivery is high, requiring careful management." "This study showed that cooperation between the two departments can raise the level of treatment for mothers with rare diseases to the next level."." Professor Kim Ho-yeon added, `We hope that this study will help establish life-saving standards for both mothers and fetuses in the future.'
The Korean Society of Obstetricians and Gynecologists is the most prestigious academic conference in the field of obstetrics and gynecologists and researchers across the country share the latest medical knowledge. This year's conference was held at the Raum Art Center in Seoul from October 30 to 31, and obstetricians and related people from all over the world attended to share the latest research results and clinical experiences in the field of obstetrics and gynecology.
The risk of stroke risk associated with the mode of delivery in women with Moyamoya disease, published by the research team, is a nationwide large-scale study comparing natural delivery and cesarean section of 1,683 mothers diagnosed with Moyamoya disease through data from the Health Insurance Review and Assessment Service from 2002 to 2023.
The study was conducted through close collaboration between neurology and obstetrics and gynecology, and by analyzing hemodynamic changes and neurological risk factors in pregnancy and delivery together, an integrated clinical basis that is difficult to obtain with a single medical department study was confirmed.
Until now, there has been no clear standard for delivery methods for mothers with moya molya disease, but cesarean section has tended to be preferred due to concerns about the risk of stroke due to changes in blood pressure during the delivery process. However, as a result of this study, there was no statistically significant difference in the risk of postpartum stroke between the two delivery methods.
This suggests the clinical basis that if proper prenatal management and monitoring are performed, mothers with moyamoya disease can also give birth naturally. In particular, this study is significant in that neurology and obstetrics jointly analyze and interpret patient data, comprehensively considering not only obstetric conditions but also cerebrovascular disease characteristics and risk factors.
In addition, the research team confirmed similar results in the analysis of age, comorbidities such as high blood pressure and diabetes, and pregnancy-related complications, supporting that there is low evidence for cesarean section just because Moya moya disease exists. The results of the study are expected to contribute to improving the guidelines for establishing customized delivery strategies for mothers with rare diseases in the future.
Professor Jeong Jin-man said, "Moya moya disease is a rare and incurable disease in which the blood vessels of the brain gradually narrow, and the risk of stroke during pregnancy and delivery is high, requiring careful management." "This study showed that cooperation between the two departments can raise the level of treatment for mothers with rare diseases to the next level."." Professor Kim Ho-yeon added, `We hope that this study will help establish life-saving standards for both mothers and fetuses in the future.'
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This article was translated by Naver AI translator.
