Extreme pain CRPS without wound or irritation, cause and treatment?
Sep 26, 2025
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Professor Lee Mi-soon of the Department of Anesthesiology and Pain Medicine at Soonchunhyang University Bucheon Hospital explained that the main symptoms of complex pain syndrome include ▲'Purplegia' that causes pain even without stimulation' ▲'Dysentilation' that causes severe pain just by touching the collar' ▲'Sensory hypersensitivity' that causes excessive pain." In addition, ▲ autonomic nervous system abnormalities such as skin temperature and color changes, sweating abnormalities, and swelling ▲ Motor nervous system functional disorders such as decreased muscle strength and restricted joint movement may also appear.
Complex pain syndrome is not explained by one cause. Over-excitement of damaged nerves, excessive operation of the sympathetic nervous system, long-term inflammatory reactions, and abnormal pain memory formation in the brain work in combination. Diagnosis is not easy because the causes are diverse and the differences between patients are large.
In particular, symptoms are similar to peripheral neuropathy, rheumatoid arthritis, and fibromyalgia, making it easy to be confused. There is no single test method to make a definitive diagnosis, so the patient's symptoms and progress are comprehensively examined and other diseases are excluded through several auxiliary tests.
Complex pain syndrome has a good prognosis only when treatment is started within 6 months after the onset. Professor Lee Mi-soon said, `When treatment is delayed, the pain circuit in the brain hardens, and structural changes such as joint stiffness and osteoporosis make recovery difficult" he warned.
In addition to medication, treatment includes nerve block, physical therapy, rehabilitation therapy, and psychotherapy, and spinal nerve stimulation is also used for intractable pain.
The biggest difficulty for patients is misunderstanding around them. Since there is no apparent problem, it is misunderstood that it is a sensitive or mental problem, and it also leads to greater stress and psychological isolation.
Professor Lee said "Complex pain syndrome is a disease that occurs due to abnormalities in the nervous system. Patients need accurate description of the disease, empathy, and social support."Medical staff should come up with an integrated treatment plan that goes beyond simple pain treatment to take into account the rehabilitation and quality of life of patients," he stressed.
About 70 to 75% of patients have improved symptoms, but 25-30% may have long-term pain and decreased function. Although complete pain loss is difficult, the realistic treatment goal is to recover to a level where daily life is possible through constant treatment.
Professor Lee explained, "Complex pain syndrome is a painful chronic disease, but it is not a hopeless disease. If you are diagnosed early and plan treatment with a professional medical staff, you can overcome it"If you continue to treat the disease based on the support of your family and society and the trust relationship with your medical staff, you will surely overcome this disease."
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This article was translated by Naver AI translator.
