After comparing endometrial cancer minimally invasive surgery, laparotomy, survival rate and complications...

Mar 27, 2025

As a result of comparing patients with minimally invasive surgery and laparotomy during endometrial cancer surgery, it was studied that there was no difference in survival rate and complications.

Minimally invasive surgery refers to laparoscopic or robotic surgery. However, in terms of the speed of recovery, minimally invasive surgery was found to be advantageous.

Professor Hwang Dong-won of obstetrics and gynecology at Ilsan Paik Hospital of Inje University and Professor Imaria of obstetrics and gynecology at Seoul National University Hospital compared survival rates and complications to 91 patients who underwent surgery for non-endometrial endometrial cancer from 2004 to 2017.




Studies showed no difference in both overall survival (OS) and disease-free survival (PFS) between the two groups. This means that both surgical methods have the same effect on the patient's survival rate.

In some indicators related to surgery, minimally invasive surgery showed favorable results over laparotomy. The mean amount of bleeding in the minimally invasive surgical group was 305.1 mL, which was significantly lower than that in the laparotomy group (561.2 mL).

The average hospitalization period was 8.2 days, 7.2 days shorter than the open surgery (15.4 days), indicating that the patient recovered quickly. The incidence of postoperative complications was 14.6% in the minimally invasive surgery group, slightly lower than in the open surgery (26.0%) group, but there was no statistically significant difference.




The research team also analyzed the major factors affecting prognosis in this study. Studies have shown that patients with lymphatic vascular infiltration (LVSI) have a threefold increased risk of disease progression and a fourfold increased risk of death. In addition, it was confirmed that patients over 60 years of age had a five-fold increase in the risk of death, indicating that closer management was needed for elderly patients.

Professor Dong-Won Hwang explained, "In the case of patients with non-endometrial endometrial cancer, minimally invasive surgery has the advantage of less bleeding and faster recovery compared to laparotomy, so minimally invasive surgery can be considered more actively when determining the surgery method.""Patients over 60 years of age or those with lymphatic vascular infiltration may have a poor prognosis, so treatment strategies should be made more closely and carefully to reflect risk factors."

Nonendometrial type endometrial cancer accounts for approximately 20% of all endometrial cancers. It is classified as a high-risk cancer with more aggressive and poor prognosis than endometrial endometrial cancer. Surgery and chemotherapy are essential because they show rapid progression and high recurrence rates. While endometrial carcinoma is associated with hormones, non-endometrial endometrial cancer has a low hormone treatment effect, so active surgical treatment and chemotherapy are important.




The paper was published in the recent issue of the SCIE-class European Journal of Surgical Oncology (IF 3.5).

After comparing endometrial cancer minimally invasive surgery, laparotomy, survival rate and complications...
Professor Hwang Dong-won's laparoscopic surgery





This article was translated by Naver AI translator.